We welcome Irina KUZNETSOVA to our group, who will do her PhD with us on the topic of machine learning for mitochondria research
Her inauguratioal talk is on
Mitochondrial diseases are progressive and debilitating multi-system disorders that occur at a frequency of up to 1 in 5,000 live births with no known cure. There is a variety of different complex mechanisms that cause the disruption of normal mitochondrial functions and leads to development of mitochondrial diseases. Identification of the molecular and pathophysiological mechanisms that cause mitochondrial disease remains challenging. However, establishing mouse models of mitochondrial disease would enable the study of the onset, progression and penetrance of mitochondrial disease as well as investigation of the tissues specifically affected in mitochondrial disease. Consequently this will enable to develop pre-clinical models of mitochondrial disease that could be used for testing a range of treatments for these diseases.
Irina did her Bachelor in computing sciences in St.Petersburg, and her Masters in Bioinformatics at the Tampere University of Technology in Finland. Curently she is working a the Mitochondrial Medicine and Biology laboratory at the University of Western Australia in Perth where she is co-supervised by Professor Aleksandra Filipovska.